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dc.identifier.urihttp://hdl.handle.net/1951/55386
dc.identifier.urihttp://hdl.handle.net/11401/70907
dc.description.sponsorshipThis work is sponsored by the Stony Brook University Graduate School in compliance with the requirements for completion of degree.en_US
dc.formatMonograph
dc.format.mediumElectronic Resourceen_US
dc.language.isoen_US
dc.publisherThe Graduate School, Stony Brook University: Stony Brook, NY.
dc.typeDissertation
dcterms.abstractThe mixture of two regression regimes has been extensively studied in economics. A switching regression is often used to model a system that changes depending on some variables. The test of a mixture of regimes in hazard modeling would be seen to have fundamental importance in biostatistical research but has not been studied. A two-regime parametric mixture is proposed to model the effect of a single covariate on the event time. Typically, the Cox proportional hazards model is applied to estimate a single regime survival regression function. The mixture of two regimes model contains five parameters to be estimated; namely, two parameters to describe each regime, and one to describe the mixing proportion. A software program developed for this research finds the maximum likelihood estimates of the parameters and the likelihood ratio test of the null hypothesis of a single regime against the alternative of a mixture of two regimes. A simulation study finds an approximation to the null distribution of the test and its approximate power.
dcterms.available2012-05-15T18:02:42Z
dcterms.available2015-04-24T14:45:04Z
dcterms.contributorReich, Nancy C.en_US
dcterms.contributorNanct Medell R. Mendellen_US
dcterms.contributorWei Zhuen_US
dcterms.contributorDerek Gordon.en_US
dcterms.creatorChen, Paichuan
dcterms.dateAccepted2012-05-15T18:02:42Z
dcterms.dateAccepted2015-04-24T14:45:04Z
dcterms.dateSubmitted2012-05-15T18:02:42Z
dcterms.dateSubmitted2015-04-24T14:45:04Z
dcterms.descriptionDepartment of Applied Mathematics and Statisticsen_US
dcterms.formatMonograph
dcterms.formatApplication/PDFen_US
dcterms.identifierhttp://hdl.handle.net/1951/55386
dcterms.identifierChen_grad.sunysb_0771E_10219.pdfen_US
dcterms.identifierhttp://hdl.handle.net/11401/70907
dcterms.issued2010-08-01
dcterms.languageen_US
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dcterms.publisherThe Graduate School, Stony Brook University: Stony Brook, NY.
dcterms.subjectexponential survival analysis, Mixture Survival Analysis, Quandt Ramsey
dcterms.subjectStatistics -- Biology, Biostatistics
dcterms.titleExtending the Quandt-Ramsey Modeling to Survival Analysis
dcterms.typeDissertation


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