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dc.identifier.urihttp://hdl.handle.net/11401/77197
dc.description.sponsorshipThis work is sponsored by the Stony Brook University Graduate School in compliance with the requirements for completion of degree.en_US
dc.formatMonograph
dc.format.mediumElectronic Resourceen_US
dc.language.isoen_US
dc.publisherThe Graduate School, Stony Brook University: Stony Brook, NY.
dc.typeDissertation
dcterms.abstractPsychiatric disorders are the most common and costly forms of disease and injury worldwide. Despite this, our ability to accurately identify and treat these disorders is limited, due in part to deficient understanding of the underlying mechanisms of dysfunction. The current study aimed to identify genetically-influenced neurobehavioral traits--individual differences evident in both self-report and neural response--that might help improve classification and treatment of mental disorders. Results from event-related potential (ERP) components sensitive to emotional content demonstrated that a) neural processing of emotional content is heritable, b) the heritable traits of heightened trait fear and behavioral disinhibition are associated with unique emotional deficits measured by ERPs--high trait fear is associated with increased attention to threat, while behavioral disinhibition is associated with decreased attention to threat and reward, and c) the association between these heritable ERPs and self-reported traits is largely due to environmental influence. The results of this study should elucidate the pathways by which genes and environment interact to infl uence normal and abnormal behavior.
dcterms.available2017-09-20T16:52:10Z
dcterms.contributorProudfit, Greg Hen_US
dcterms.contributorMohanty, Aprajitaen_US
dcterms.contributorLuhmann, Christianen_US
dcterms.contributorPatrick, Christopher.en_US
dcterms.creatorWeinberg, Anna EF
dcterms.dateAccepted2017-09-20T16:52:10Z
dcterms.dateSubmitted2017-09-20T16:52:10Z
dcterms.descriptionDepartment of Clinical Psychology.en_US
dcterms.extent106 pg.en_US
dcterms.formatApplication/PDFen_US
dcterms.formatMonograph
dcterms.identifierhttp://hdl.handle.net/11401/77197
dcterms.issued2014-12-01
dcterms.languageen_US
dcterms.provenanceMade available in DSpace on 2017-09-20T16:52:10Z (GMT). No. of bitstreams: 1 Weinberg_grad.sunysb_0771E_11752.pdf: 2002326 bytes, checksum: b06e6fb7cb19322eccc4972a9611e7f1 (MD5) Previous issue date: 1en
dcterms.publisherThe Graduate School, Stony Brook University: Stony Brook, NY.
dcterms.subjectERP, LPP, Neurobehavioral traits, Twin samples
dcterms.subjectPsychology
dcterms.titleEvidence for genetic contributions to neurobehavioral traits: Trait Fear/Fearlessness, Behavioral Inhibition, and the Late Positive Potential
dcterms.typeDissertation


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